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About Us

Our Company

Founded in 2017 at the Sheba Medical Center, the largest hospital in Israel and recognized among the top 10 in the world by Newsweek in 2019, 2020, 2021, and a teaching hospital of Tel Aviv University. Innovalve’s presence at Sheba’s Heart Center allows for a close collaboration with Sheba’s clinicians, developers and other professionals, along with available access to surgical and interventional cardiology expertise.

Our Leadership

The company is led by experienced managers in the field of biomedical devices and interventional cardiology, and is consulted by an extensive network of global experts, as well as an internationally recognized Scientific Advisory Board.

Founders

Ehud Raanani

PROF. EHUD RAANANI

MD, CO-FOUNDER & CHIEF SCIENTIFIC OFFICER

Prof. Raanani has vast experience in the cardiothoracic field, serves as Director of the Leviev Cardiothoracic

Boris Orlov

DR. BORIS ORLOV

MD, CO-FOUNDER

Dr. Orlov is a world-wide inventor in the cardiac field, works as a cardiac surgeon and is the Director of

Management

Eyal Bror

EYAL BAROR

CEO

Eyal has more than 15 years of
experience in managing Hi-Tech
companies and since January 2020…

Orna Landau

ORNA LANDAU

DIRECTOR OF QA / RA

Orna has more than 12 years of experience in the medical device and pharmaceutical industry, and 6 years…

Guy Shimel

GUY SHIMEL

DELIVERY SYSTEMS R&D MANAGER

R&D Team leader – Mechanical Engineer (M.Sc.) with 10 years of experience providing effective…

Natasha Kruglova

NATALIA KRUGLOV

OPERATIONS MANAGER

15 years of professional experience in the field of Medical Devices and R&D Lab, participating in design…

Miriam Ivenshitz

MIRIAM IVENSHITZ

DIRECTOR OF CLINICAL AFFAIRS

Miriam brings with her more than a
decade of experience in medical
device clinical trial activity, including…

Shai Karni

SHAI KARNI

VALVE DEVELOPMENT MANAGER

Over 10 years of experience developing cardiovascular medical devices for valve repair and…

Yonatan-Greenberg

YONATAN GREENBERG

DIRECTOR OF OPERATIONS AND ENGINEERING

Yonatan has more than 15 years of experience in product development with 10 years from…

Our Vision

Our vision is to provide physicians and patients with new non-surgical modalities for safe and effective treatment of heart valve morbidities, in particular – mitral valve regurgitation.

The introduction of novel catheter technologies to replace a defective mitral valve may dramatically alter the existing approach for treating mitral regurgitation. Innovalve’s TMVR System will allow physicians to offer therapy to patients who suffer from mitral regurgitation, and who currently have no good and safe solution/intervention for their condition. Innovalve’s TMVR System has the ability to transform these patients markets from either surgery-based or repair-only options, to include minimally invasive TMVR. Thus, providing clinical benefit comparable to mitral valve replacement surgery, with the lower risks associated with a minimally invasive approach.

Shai Karni

SHAI KARNI

VALVE DEVELOPMENT MANAGER

Over 10 years of experience developing cardiovascular medical devices for valve repair and replacement, bringing ideas from concept to clinical readiness. Shai started his career at Edwards Lifesciences working on innovative Mitral and Aortic projects and later worked for several startups before joining Innovalve BioMedical to lead the design and development of Innovalve’s novel Valve.

Miriam Ivenshitz

MIRIAM IVENSHITZ

DIRECTOR OF CLINICAL AFFAIRS

Miriam brings with her more than a decade of experience in medical device clinical trial activity, including FIH and pivotal RCT trials. Prior to joining Innovalve, Miriam served in senior management roles in cardiology device companies such as CathWorks, where she led the clinical activity through successful FDA and PMDA market clearances, and InspireMD, where she oversaw the company’s clinical trials.

Dr. Ivenshitz holds a Ph.D. in Neurobiology and completed postdoctoral studies, both from the Weizmann Institute of Science, and a M.Sc in Neurobiology from Ben-Gurion University of the Negev.

Natasha Kruglova

NATALIA KRUGLOV

OPERATIONS MANAGER

Natasha has more than 15 years of professional experience in the field of Medical Devices and R&D where she was involved in design, development and manufacturing in aortic and mitral valve projects.

Prior to her work at Innovalve, Mrs. Kruglov she worked at Ventor (Medtronic) and Cardiovalve (Valtech).

Guy Shimel

GUY SHIMEL

DELIVERY SYSTEMS R&D MANAGER

R&D Team leader – Mechanical Engineer (M.Sc.) with 10 years of experience providing effective solutions in a multidisciplinary environment. Experience in medical devices field: R&D product development from early feasibility to clinical studies, specializing in delivery systems and catheter development.

Orna Landau

ORNA LANDAU

DIRECTOR OF QA / RA

Orna has more than 12 years of experience in the medical device and pharmaceutical industry, and 6 years in managing quality and regulatory affairs. Prior to Innovalve, Ms. Landau managed the quality and regulatory affairs at OCON Medical for almost 4 years.
Ms. Landau holds a BSc. in Biotechnology and MA in law from Bar-Ilan University.

Yonatan-Greenberg

YONATAN GREENBERG

TMVR SYSTEM MANAGER
Yonatan has more than 15 years of experience in product development with 10 years from within the medical device industry. Developing medical devices from concept to market, Yonatan has been managing R&D and Engineering teams developing implant and emergency care devices.

Yonatan holds a BSc in Mechanical Engineering and a BioMed MBA from the Hebrew University.

Eyal Bror

EYAL BAROR

CEO

Eyal has more than 15 years of experience in managing Hi-Tech companies and since January 2020 serves as the company’s CEO. Prior to leading Innovalve, Mr. Baror was the CEO of Neuronix Ltd for more than 10 years and PerfAction Technologies Ltd for almost 4 years.
Mr. Baror holds a B.Sc in Physics and Mathematics from Hebrew University of Jerusalem and a M.Sc in Physics from Tel-Aviv University, and is a graduate of the TALPIOT program.

Boris Orlov

DR. BORIS ORLOV

MD, CO-FOUNDER

Dr. Orlov is a world-wide inventor in the cardiac field, works as a cardiac surgeon and is the Director of Ischemic Mitral Valve Surgery Service at Sheba Medical Center. Throughout his career, Dr. Orlov wrote over 40 patents.

Ehud Raanani

PROF. EHUD RAANANI

MD, CO-FOUNDER & CHIEF SCIENTIFIC OFFICER

Prof. Raanani has vast experience in the cardiothoracic field, serves as Director of the Leviev Cardiothoracic and Vascular Center in Sheba Medical Center and Chairman of the Israel Society for Cardiothoracic Surgery. Moreover, Prof. Raanani is a lecturer in Tel-Aviv University’s Faculty for Medicine, and a member of the AATS – American Association of Thoracic Surgeons and EACTS – European Society for Cardio-Thoracic Surgery.